Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOR53_744ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (179 aa)    
Predicted Functional Partners:
gstch
[O] COG0625 Glutathione S-transferase.
  
  
  0.703
gshB
Glutathione synthase; [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the prokaryotic GSH synthase family.
     
 0.666
pepA
Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.647
EED32663.1
Conserved hypothetical protein TIGR00370; [E] COG2049 Allophanate hydrolase subunit 1.
     
  0.647
EED33537.1
[O] COG0625 Glutathione S-transferase.
     
  0.647
EED33745.1
Glutathione S-transferase, N-terminal domain; [O] COG0625 Glutathione S-transferase.
     
  0.647
EED32664.1
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.647
EED31511.1
[O] COG0386 Glutathione peroxidase; Belongs to the glutathione peroxidase family.
     
  0.647
gor
Glutathione reductase; Maintains high levels of reduced glutathione.
     
  0.647
NOR53_660
Putative Glutathione S-transferase family protein; [O] COG0625 Glutathione S-transferase.
  
  
  0.647
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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