Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysMCysteine synthase B; [E] COG0498 Threonine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (308 aa)    
Predicted Functional Partners:
cysE
[R] COG0110 Acetyltransferase (isoleucine patch superfamily).
 
 0.996
cysS
[J] COG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.944
metC
[E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 0.942
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 0.942
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.910
EED32990.1
Sulphite reductase; [C] COG2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits.
  
 
 0.910
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
  0.845
EED33782.1
Thiosulfate sulfurtransferase (Rhodanese); [P] COG2897 Rhodanese-related sulfurtransferase.
  
 
 0.832
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.817
EED32118.1
[E] COG0620 Methionine synthase II (cobalamin-independent).
   
 
 0.809
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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