STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mgtEMagnesium transporter; Acts as a magnesium transporter. (450 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr; [G] COG1925 Phosphotransferase system, HPr-related proteins.
     
 0.820
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.812
EED33891.1
[S] COG3028 Uncharacterized protein conserved in bacteria; Belongs to the UPF0307 family.
       0.799
NOR53_694
Nitrogen regulatory protein (Enzyme IIA-NTR); [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
 
   
 0.770
NOR53_699
Conserved hypothetical protein; Displays ATPase and GTPase activities.
       0.731
raiA
Ribosomal subunit interface protein; [J] COG1544 Ribosome-associated protein Y (PSrp-1).
       0.731
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.706
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.623
purH
Bifunctional purine biosynthesis protein PurH; [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).
    
 0.599
EED33880.1
Arabinose 5-phosphate isomerase; [M] COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains.
    
  0.591
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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