Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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[Homology]
Score
NOR53_853[L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (183 aa)    
Predicted Functional Partners:
EED32648.1
Cyclic nucleotide-binding protein; [R] COG0517 FOG: CBS domain.
 
  0.961
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.828
dnaX
DNA polymerase III, tau and gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 0.820
EED32466.1
[L] COG2176 DNA polymerase III, alpha subunit (gram-positive type).
    
 0.770
holA
[L] COG1466 DNA polymerase III, delta subunit.
    
 0.764
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
  
  
  0.747
EED32646.1
Sodium/solute symporter family protein; [ER] COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.744
holB
[L] COG2812 DNA polymerase III, gamma/tau subunits.
    
  0.743
dnaE2
Putative DNA polymerase III alpha subunit subfamily; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
    
 0.736
rnd
[J] COG0349 Ribonuclease D.
   
 0.704
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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