Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (368 aa)    
Predicted Functional Partners:
hflD
Conserved hypothetical protein; [R] COG2915 Uncharacterized protein involved in purine metabolism.
  
  
 0.974
trmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 0.942
EED33033.1
Sulfurtransferase TusE; Part of a sulfur-relay system.
   
 0.935
gidA
tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
 
 0.922
tusD
Sulfur relay protein TusD/DsrE; [P] COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction.
    
 0.913
NOR53_879
DsrE/DsrF-like family protein; [P] COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur.
    
 0.875
dsrH
Sulfur relay protein TusB/DsrH.
    
 0.862
EED32603.1
Cysteine desulfurase; [R] COG1103 Archaea-specific pyridoxal phosphate-dependent enzymes.
  
 
 0.842
dndA
Cysteine desulfurase DndA; [E] COG0520 Selenocysteine lyase.
  
 
 0.842
NOR53_870
Adenylyltransferase; [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
  
 
 0.798
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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