| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED32226.1 | EED32969.1 | NOR53_2965 | NOR53_1810 | [E] COG0070 Glutamate synthase domain 3. | Sulfide:quinone oxidoreductase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | 0.783 |
| EED32226.1 | EED34003.1 | NOR53_2965 | NOR53_1705 | [E] COG0070 Glutamate synthase domain 3. | Sulfide dehydrogenase (flavocytochrome c) flavoprotein chain; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | 0.783 |
| EED32226.1 | NOR53_906 | NOR53_2965 | NOR53_906 | [E] COG0070 Glutamate synthase domain 3. | N-methyl-l-tryptophan oxidase (mtox); [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.783 |
| EED32226.1 | gcvP | NOR53_2965 | NOR53_1476 | [E] COG0070 Glutamate synthase domain 3. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.837 |
| EED32226.1 | gcvT | NOR53_2965 | NOR53_3330 | [E] COG0070 Glutamate synthase domain 3. | [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase). | 0.849 |
| EED32226.1 | glyA | NOR53_2965 | NOR53_320 | [E] COG0070 Glutamate synthase domain 3. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.822 |
| EED32226.1 | metH | NOR53_2965 | NOR53_1222 | [E] COG0070 Glutamate synthase domain 3. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.450 |
| EED32969.1 | EED32226.1 | NOR53_1810 | NOR53_2965 | Sulfide:quinone oxidoreductase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | [E] COG0070 Glutamate synthase domain 3. | 0.783 |
| EED32969.1 | EED34003.1 | NOR53_1810 | NOR53_1705 | Sulfide:quinone oxidoreductase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | Sulfide dehydrogenase (flavocytochrome c) flavoprotein chain; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | 0.724 |
| EED32969.1 | NOR53_906 | NOR53_1810 | NOR53_906 | Sulfide:quinone oxidoreductase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | N-methyl-l-tryptophan oxidase (mtox); [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.635 |
| EED32969.1 | gcvP | NOR53_1810 | NOR53_1476 | Sulfide:quinone oxidoreductase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.795 |
| EED32969.1 | gcvT | NOR53_1810 | NOR53_3330 | Sulfide:quinone oxidoreductase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase). | 0.471 |
| EED32969.1 | glyA | NOR53_1810 | NOR53_320 | Sulfide:quinone oxidoreductase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.544 |
| EED33742.1 | NOR53_906 | NOR53_1145 | NOR53_906 | Low specificity L-threonine aldolase; [E] COG2008 Threonine aldolase. | N-methyl-l-tryptophan oxidase (mtox); [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.631 |
| EED33742.1 | gcvP | NOR53_1145 | NOR53_1476 | Low specificity L-threonine aldolase; [E] COG2008 Threonine aldolase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.849 |
| EED33742.1 | gcvT | NOR53_1145 | NOR53_3330 | Low specificity L-threonine aldolase; [E] COG2008 Threonine aldolase. | [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase). | 0.675 |
| EED33742.1 | glyA | NOR53_1145 | NOR53_320 | Low specificity L-threonine aldolase; [E] COG2008 Threonine aldolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.743 |
| EED34003.1 | EED32226.1 | NOR53_1705 | NOR53_2965 | Sulfide dehydrogenase (flavocytochrome c) flavoprotein chain; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | [E] COG0070 Glutamate synthase domain 3. | 0.783 |
| EED34003.1 | EED32969.1 | NOR53_1705 | NOR53_1810 | Sulfide dehydrogenase (flavocytochrome c) flavoprotein chain; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | Sulfide:quinone oxidoreductase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | 0.724 |
| EED34003.1 | NOR53_906 | NOR53_1705 | NOR53_906 | Sulfide dehydrogenase (flavocytochrome c) flavoprotein chain; [C] COG1252 NADH dehydrogenase, FAD-containing subunit. | N-methyl-l-tryptophan oxidase (mtox); [E] COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.624 |