Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NOR53_922[V] COG1715 Restriction endonuclease. (301 aa)    
Predicted Functional Partners:
NOR53_461
EcoEI R C-terminal domain protein; [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
 
  
 0.701
hsdM
[V] COG0286 Type I restriction-modification system methyltransferase subunit.
 
  
 0.687
EED33279.1
Hypothetical protein.
       0.598
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
      
 0.473
galU
UTP-glucose-1-phosphate uridylyltransferase; [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).
      
 0.472
EED33429.1
Galactokinase; [I] COG1577 Mevalonate kinase; Belongs to the GHMP kinase family. GalK subfamily.
      
 0.468
NOR53_449
Restriction modification system DNA specificity domain protein; [V] COG0732 Restriction endonuclease S subunits.
 
  
 0.432
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (14%) [HD]