Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1166 aa)    
Predicted Functional Partners:
EED33774.1
ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
 
 0.916
EED31684.1
Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase.
   
 0.824
EED33773.1
Chromosome segregation and condensation protein ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
 
 
 
 0.810
NOR53_215
[T] COG0642 Signal transduction histidine kinase.
   
 0.791
EED33682.1
[T] COG0642 Signal transduction histidine kinase.
   
 0.761
ligA_1
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
  
    0.677
NOR53_559
Diguanylate cyclaSe/phosphodiesterase with PAS/PAC sensor(s); [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins.
    
 0.674
EED34033.1
CheB methylesterase/CheR methyltransferase; [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
  
 
 0.661
EED32792.1
Hypothetical protein.
  
    0.631
zipA
ZipA, C-terminal FtsZ-binding domain; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
    0.600
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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