| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31895.1 | NOR53_967 | NOR53_3287 | NOR53_967 | Transcriptional regulator, ArsR family; [K] COG0640 Predicted transcriptional regulators. | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | 0.598 |
| EED31895.1 | coq7 | NOR53_3287 | NOR53_505 | Transcriptional regulator, ArsR family; [K] COG0640 Predicted transcriptional regulators. | Ubiquinone biosynthesis protein COQ7; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | 0.695 |
| EED31895.1 | gcvP | NOR53_3287 | NOR53_1476 | Transcriptional regulator, ArsR family; [K] COG0640 Predicted transcriptional regulators. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.697 |
| EED31895.1 | metH | NOR53_3287 | NOR53_1222 | Transcriptional regulator, ArsR family; [K] COG0640 Predicted transcriptional regulators. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.697 |
| EED32519.1 | NOR53_967 | NOR53_2302 | NOR53_967 | [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | 0.485 |
| EED32519.1 | chlD | NOR53_2302 | NOR53_1137 | [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. | Protoporphyrin IX Magnesium chelatase subunit ChlD; [H] COG1239 Mg-chelatase subunit ChlI. | 0.853 |
| EED32632.1 | EED32633.1 | NOR53_1867 | NOR53_1135 | Serine carboxypeptidase family protein; [E] COG2939 Carboxypeptidase C (cathepsin A). | [S] COG3391 Uncharacterized conserved protein. | 0.559 |
| EED32632.1 | NOR53_967 | NOR53_1867 | NOR53_967 | Serine carboxypeptidase family protein; [E] COG2939 Carboxypeptidase C (cathepsin A). | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | 0.516 |
| EED32633.1 | EED32632.1 | NOR53_1135 | NOR53_1867 | [S] COG3391 Uncharacterized conserved protein. | Serine carboxypeptidase family protein; [E] COG2939 Carboxypeptidase C (cathepsin A). | 0.559 |
| EED32633.1 | NOR53_967 | NOR53_1135 | NOR53_967 | [S] COG3391 Uncharacterized conserved protein. | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | 0.741 |
| NOR53_967 | EED31895.1 | NOR53_967 | NOR53_3287 | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | Transcriptional regulator, ArsR family; [K] COG0640 Predicted transcriptional regulators. | 0.598 |
| NOR53_967 | EED32519.1 | NOR53_967 | NOR53_2302 | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. | 0.485 |
| NOR53_967 | EED32632.1 | NOR53_967 | NOR53_1867 | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | Serine carboxypeptidase family protein; [E] COG2939 Carboxypeptidase C (cathepsin A). | 0.516 |
| NOR53_967 | EED32633.1 | NOR53_967 | NOR53_1135 | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | [S] COG3391 Uncharacterized conserved protein. | 0.741 |
| NOR53_967 | chlD | NOR53_967 | NOR53_1137 | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | Protoporphyrin IX Magnesium chelatase subunit ChlD; [H] COG1239 Mg-chelatase subunit ChlI. | 0.753 |
| NOR53_967 | coq7 | NOR53_967 | NOR53_505 | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | Ubiquinone biosynthesis protein COQ7; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | 0.562 |
| NOR53_967 | gcvP | NOR53_967 | NOR53_1476 | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.657 |
| NOR53_967 | glyA | NOR53_967 | NOR53_320 | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.524 |
| NOR53_967 | metH | NOR53_967 | NOR53_1222 | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.525 |
| NOR53_967 | mnmC | NOR53_967 | NOR53_1193 | Methyltransferase type 11; [QR] COG0500 SAM-dependent methyltransferases. | Oxidoreductase, FAD-binding; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.493 |