Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ppx[FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. (514 aa)    
Predicted Functional Partners:
ppk_2
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
 
 0.927
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
   
 
 0.844
ppk_1
Polyphosphate kinase 2; [S] COG2326 Uncharacterized conserved protein.
 
 
 0.713
EED32344.1
PvdS; [S] COG2326 Uncharacterized conserved protein.
 
 
 0.713
pstA
Phosphate ABC transporter, permease protein PstA; [P] COG4208 ABC-type sulfate transport system, permease component.
     
 0.705
EED32631.1
[S] COG1507 Uncharacterized conserved protein.
  
 
  0.618
spoT_2
Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; overlaps another CDS with the same product name.
   
 
 0.604
spoT_1
Guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
   
 
 0.604
ppa
[C] COG0221 Inorganic pyrophosphatase.
     
 0.577
EED32082.1
[P] COG0306 Phosphate/sulphate permeases.
     
 0.548
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.