Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NOR53_990Aminotransferase, class I and II; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase. (395 aa)    
Predicted Functional Partners:
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
    
 0.845
EED33454.1
Putative Phosphate acetyl/butyryl transferase subfamily; [C] COG0281 Malic enzyme.
 
 0.782
EED32422.1
2-oxoacid:ferredoxin/flavodoxin oxidoreductase, gamma subunit domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
 
  
 0.677
EED33765.1
P-protein; [E] COG1605 Chorismate mutase.
  
 
 0.647
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
 0.620
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.615
putA_1
Bifunctional PutA protein; [C] COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase.
     
 0.615
EED31664.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
  
 
 0.607
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.598
EED31826.1
Glyoxylate reductase; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.595
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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