Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rubB_1[C] COG1251 NAD(P)H-nitrite reductase; Belongs to the FAD-dependent oxidoreductase family. (451 aa)    
Predicted Functional Partners:
EED33801.1
Rubredoxin; [C] COG1773 Rubredoxin; Belongs to the rubredoxin family.
  
 0.983
rubB_2
Rubredoxin reductase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Belongs to the FAD-dependent oxidoreductase family.
  
 0.983
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
  
 
 0.871
EED33372.1
Rieske (2Fe-2S) domain protein; [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.
  
 
 0.860
EED31392.1
Putative Rieske [2Fe-2S] domain; [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.
  
 
 0.860
NOR53_861
Putative Rieske (2Fe-2S) domain protein; [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.
  
 
 0.860
EED32850.1
Reductive dehalogenase; [C] COG1600 Uncharacterized Fe-S protein.
  
 
 0.816
EED32854.1
Alkyl sulfatase or beta-lactamase; [R] COG0491 Zn-dependent hydrolases, including glyoxylases.
  
    0.776
EED32990.1
Sulphite reductase; [C] COG2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits.
   
 0.766
EED31664.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
    
 0.761
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (20%) [HD]