STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPF20317.15-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1227 aa)    
Predicted Functional Partners:
EPF12670.1
KEGG: kpu:KP1_0102 2.5e-148 metF; 5,10-methylenetetrahydrofolate reductase; K00297 methylenetetrahydrofolate reductase (NADPH); Psort location: Cytoplasmic, score: 9.97.
 
 
 0.998
EPF20729.1
Homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.984
EPF12669.1
Homoserine dehydrogenase; KEGG: esa:ESA_03821 0. metL; bifunctional aspartate kinase II/homoserine dehydrogenase II; K12525 bifunctional aspartokinase/homoserine dehydrogenase 2; Psort location: CytoplasmicMembrane, score: 9.27; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.984
EPF17586.1
Methionine synthase, vitamin-B12 independent; KEGG: spe:Spro_3176 1.1e-152 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; K00549 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.967
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.967
EPF16872.1
KEGG: kva:Kvar_0681 5.2e-164 cystathionine gamma-lyase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.964
EPF13806.1
KEGG: ent:Ent638_3418 1.6e-183 cystathionine beta-lyase K01760; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.964
EPF13859.1
KEGG: cro:ROD_48281 1.8e-184 metC; cystathionine beta-lyase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.964
EPF12668.1
KEGG: ent:Ent638_4035 3.0e-191 cystathionine gamma-synthase K01739; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.964
EPF20634.1
S-adenosyl-L-homocysteine hydrolase, NAD binding domain protein.
  
 
 0.945
Your Current Organism:
Cedecea davisae
NCBI taxonomy Id: 566551
Other names: C. davisae DSM 4568, Cedecea davisae ATCC 33431, Cedecea davisae DSM 4568, Cedecea davisae str. DSM 4568, Cedecea davisae strain 005, Cedecea davisae strain DSM 4568
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