STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LINJ_03_0190Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (560 aa)    
Predicted Functional Partners:
LINJ_26_1590
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
  
 0.989
LINJ_26_2740
Putative glutamate 5-kinase.
  
 
 0.976
LINJ_32_3340
Pyrroline-5-carboxylate synthetase-like protein.
  
 
 0.976
GDH
NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.949
LINJ_28_3140
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.949
LINJ_24_0370
Putative aspartate aminotransferase.
   
 0.946
asat
Putative aspartate aminotransferase.
   
 0.946
P5CR
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
   
 0.941
LINJ_06_0370
Putative glutamine synthetase; Belongs to the glutamine synthetase family.
  
 
 0.925
GCVL-1
Putative dihydrolipoamide dehydrogenase.
  
 
 0.860
Your Current Organism:
Leishmania infantum
NCBI taxonomy Id: 5671
Other names: L. infantum, Leishmania (Leishmania) infantum, Leishmania donovani infantum
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