LINJ_22_0480 protein (Leishmania infantum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LINJ_22_0480

Ubiquitin-conjugating enzyme-like protein. (260 aa)

Predicted Functional Partners:

LINJ_35_2900

0.951

LINJ_23_0710

0.882

LINJ_35_3110

0.882

LINJ_13_1320

0.875

LINJ_14_1350

0.829

LINJ_36_0660

0.829

LINJ_31_1930

0.822

LINJ_09_0790

0.819

LINJ_15_1500

0.793

LINJ_32_1150

0.792

Your Current Organism:

Leishmania infantum

NCBI taxonomy Id: 5671
Other names: L. infantum, Leishmania (Leishmania) infantum, Leishmania donovani infantum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LINJ_09_0790	LINJ_14_1350	A4HTZ5	A4HW73	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Putative ubiquitin/ribosomal protein S27a.	0.589
LINJ_09_0790	LINJ_22_0480	A4HTZ5	A4HZT8	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Ubiquitin-conjugating enzyme-like protein.	0.819
LINJ_09_0790	LINJ_31_1930	A4HTZ5	E9AHL5	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Ubiquitin-fusion protein.	0.526
LINJ_09_0790	LINJ_32_1150	A4HTZ5	A4I7S6	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Uncharacterized protein.	0.990
LINJ_09_0790	LINJ_36_0660	A4HTZ5	A4ICS4	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	Putative ubiquitin/ribosomal protein S27a.	0.589
LINJ_13_1320	LINJ_14_1350	A4HVS0	A4HW73	Ubiquitin-conjugating enzyme-like protein.	Putative ubiquitin/ribosomal protein S27a.	0.894
LINJ_13_1320	LINJ_15_1500	A4HVS0	A4HWN2	Ubiquitin-conjugating enzyme-like protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.860
LINJ_13_1320	LINJ_22_0480	A4HVS0	A4HZT8	Ubiquitin-conjugating enzyme-like protein.	Ubiquitin-conjugating enzyme-like protein.	0.875
LINJ_13_1320	LINJ_23_0710	A4HVS0	A4I0A5	Ubiquitin-conjugating enzyme-like protein.	Putative ubiquitin-activating enzyme e1; Belongs to the ubiquitin-activating E1 family.	0.725
LINJ_13_1320	LINJ_31_1930	A4HVS0	E9AHL5	Ubiquitin-conjugating enzyme-like protein.	Ubiquitin-fusion protein.	0.990
LINJ_13_1320	LINJ_35_3110	A4HVS0	A4IBJ4	Ubiquitin-conjugating enzyme-like protein.	Putative ubiquitin-activating enzyme e1.	0.725
LINJ_13_1320	LINJ_36_0660	A4HVS0	A4ICS4	Ubiquitin-conjugating enzyme-like protein.	Putative ubiquitin/ribosomal protein S27a.	0.894
LINJ_14_1350	LINJ_09_0790	A4HW73	A4HTZ5	Putative ubiquitin/ribosomal protein S27a.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.589
LINJ_14_1350	LINJ_13_1320	A4HW73	A4HVS0	Putative ubiquitin/ribosomal protein S27a.	Ubiquitin-conjugating enzyme-like protein.	0.894
LINJ_14_1350	LINJ_15_1500	A4HW73	A4HWN2	Putative ubiquitin/ribosomal protein S27a.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.889
LINJ_14_1350	LINJ_22_0480	A4HW73	A4HZT8	Putative ubiquitin/ribosomal protein S27a.	Ubiquitin-conjugating enzyme-like protein.	0.829
LINJ_14_1350	LINJ_23_0710	A4HW73	A4I0A5	Putative ubiquitin/ribosomal protein S27a.	Putative ubiquitin-activating enzyme e1; Belongs to the ubiquitin-activating E1 family.	0.864
LINJ_14_1350	LINJ_31_1930	A4HW73	E9AHL5	Putative ubiquitin/ribosomal protein S27a.	Ubiquitin-fusion protein.	0.993
LINJ_14_1350	LINJ_32_1150	A4HW73	A4I7S6	Putative ubiquitin/ribosomal protein S27a.	Uncharacterized protein.	0.752
LINJ_14_1350	LINJ_35_2900	A4HW73	A4IBH3	Putative ubiquitin/ribosomal protein S27a.	Uncharacterized protein.	0.925