Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cln8CLN8 transmembrane ER and ERGIC protein. (288 aa)    
Predicted Functional Partners:
cln6
CLN6 transmembrane ER protein.
      
 0.874
cln5
CLN5 intracellular trafficking protein.
      
 0.865
ppt1
Palmitoyl-protein thioesterase 1.
      
 0.846
mfsd8
Major facilitator superfamily domain containing 8.
      
 0.846
cln3
CLN3 lysosomal/endosomal transmembrane protein, battenin.
      
 0.846
tpp1
Tripeptidyl peptidase 1.
    
 
 0.756
lrguk
Leucine rich repeats and guanylate kinase domain containing.
    
 
 0.705
arsg
Arylsulfatase G.
      
 0.682
LOC115014945
Cathepsin F-like.
      
 0.673
atp13a2
ATPase cation transporting 13A2.
      
 0.671
Your Current Organism:
Cottoperca gobio
NCBI taxonomy Id: 56716
Other names: Aphritis gobio, C. gobio
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