Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC115007721Cyclin-dependent kinase inhibitor 1-like. (182 aa)    
Predicted Functional Partners:
skp2
S-phase kinase associated protein 2.
    
 0.993
cdk2
Cyclin dependent kinase 2.
   
 0.991
ccne1
Cyclin E1.
   
 0.989
cdk4
Cyclin dependent kinase 4.
   
 0.989
CCNE2
G1/S-specific cyclin-E2-like.
   
 0.987
LOC115009127
G1/S-specific cyclin-D1-like.
   
 0.987
cdk6
Cyclin dependent kinase 6.
   
 0.987
LOC115021414
G1/S-specific cyclin-E2-like.
   
 0.987
ccnd1
Cyclin D1.
   
 0.987
ccna1
Cyclin A1.
   
 0.987
Your Current Organism:
Cottoperca gobio
NCBI taxonomy Id: 56716
Other names: Aphritis gobio, C. gobio
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