ENSLBEP00000002417 protein (Labrus bergylta)

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second shell of interactors

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proteins of unknown 3D structure

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Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

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[Homology]

Score

ENSLBEP00000002417

C-type lectin domain-containing protein. (159 aa)

Predicted Functional Partners:

ENSLBEP00000001163

0.413

ENSLBEP00000012652

0.413

tnn

0.413

tnr

0.413

tnc

0.413

ENSLBEP00000035454

0.413

ENSLBEP00000035471

0.413

LOC109979877

0.413

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000001163	ENSLBEP00000002417	ENSLBEP00000001163	ENSLBEP00000002417	Tenascin C.	C-type lectin domain-containing protein.	0.413
ENSLBEP00000001163	ENSLBEP00000012652	ENSLBEP00000001163	ENSLBEP00000012652	Tenascin C.	Fibrinogen C-terminal domain-containing protein.	0.710
ENSLBEP00000001163	ENSLBEP00000035454	ENSLBEP00000001163	ENSLBEP00000035454	Tenascin C.	Uncharacterized protein.	0.710
ENSLBEP00000001163	ENSLBEP00000035471	ENSLBEP00000001163	ENSLBEP00000035471	Tenascin C.	Uncharacterized protein.	0.824
ENSLBEP00000001163	LOC109979877	ENSLBEP00000001163	ENSLBEP00000038856	Tenascin C.	Uncharacterized protein.	0.712
ENSLBEP00000001163	tnc	ENSLBEP00000001163	ENSLBEP00000031036	Tenascin C.	Zmp:0000000846.	0.714
ENSLBEP00000001163	tnn	ENSLBEP00000001163	ENSLBEP00000023121	Tenascin C.	Tenascin N.	0.816
ENSLBEP00000001163	tnr	ENSLBEP00000001163	ENSLBEP00000023357	Tenascin C.	Tenascin R (restrictin, janusin).	0.824
ENSLBEP00000002417	ENSLBEP00000001163	ENSLBEP00000002417	ENSLBEP00000001163	C-type lectin domain-containing protein.	Tenascin C.	0.413
ENSLBEP00000002417	ENSLBEP00000012652	ENSLBEP00000002417	ENSLBEP00000012652	C-type lectin domain-containing protein.	Fibrinogen C-terminal domain-containing protein.	0.413
ENSLBEP00000002417	ENSLBEP00000035454	ENSLBEP00000002417	ENSLBEP00000035454	C-type lectin domain-containing protein.	Uncharacterized protein.	0.413
ENSLBEP00000002417	ENSLBEP00000035471	ENSLBEP00000002417	ENSLBEP00000035471	C-type lectin domain-containing protein.	Uncharacterized protein.	0.413
ENSLBEP00000002417	LOC109979877	ENSLBEP00000002417	ENSLBEP00000038856	C-type lectin domain-containing protein.	Uncharacterized protein.	0.413
ENSLBEP00000002417	tnc	ENSLBEP00000002417	ENSLBEP00000031036	C-type lectin domain-containing protein.	Zmp:0000000846.	0.413
ENSLBEP00000002417	tnn	ENSLBEP00000002417	ENSLBEP00000023121	C-type lectin domain-containing protein.	Tenascin N.	0.413
ENSLBEP00000002417	tnr	ENSLBEP00000002417	ENSLBEP00000023357	C-type lectin domain-containing protein.	Tenascin R (restrictin, janusin).	0.413
ENSLBEP00000012652	ENSLBEP00000001163	ENSLBEP00000012652	ENSLBEP00000001163	Fibrinogen C-terminal domain-containing protein.	Tenascin C.	0.710
ENSLBEP00000012652	ENSLBEP00000002417	ENSLBEP00000012652	ENSLBEP00000002417	Fibrinogen C-terminal domain-containing protein.	C-type lectin domain-containing protein.	0.413
ENSLBEP00000012652	ENSLBEP00000035454	ENSLBEP00000012652	ENSLBEP00000035454	Fibrinogen C-terminal domain-containing protein.	Uncharacterized protein.	0.969
ENSLBEP00000012652	ENSLBEP00000035471	ENSLBEP00000012652	ENSLBEP00000035471	Fibrinogen C-terminal domain-containing protein.	Uncharacterized protein.	0.962

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

45

average node degree:

8.18

avg. local clustering coefficient:

0.879

expected number of edges:

14

PPI enrichment p-value:

5.11e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

6 of 12

1.81

2.66

5.30e-07

GO:0031564

Transcription antitermination

3 of 3

2.11

1.69

0.00052

GO:0006353

DNA-templated transcription, termination

3 of 3

2.11

1.69

0.00052

GO:0016070

RNA metabolic process

7 of 75

1.08

1.11

5.42e-05

GO:0010467

Gene expression

9 of 136

0.93

0.97

7.65e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003899

DNA-directed 5-3 RNA polymerase activity

3 of 4

1.99

1.31

0.0028

GO:0003676

Nucleic acid binding

8 of 177

0.77

0.59

0.0028

GO:0140098

Catalytic activity, acting on RNA

4 of 48

1.03

0.58

0.0311

GO:0003723

RNA binding

4 of 62

0.92

0.49

0.0476

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000428

DNA-directed RNA polymerase complex

3 of 5

1.89

1.38

0.0017

GO:0032991

Protein-containing complex

4 of 77

0.83

0.48

0.0351

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:220

RNA polymerase, and Transcription antitermination

5 of 5

2.11

3.01

5.81e-07

CL:138

Ribonucleoprotein

6 of 46

1.23

1.34

3.47e-05

CL:135

Ribonucleoprotein, and Translation regulator activity

7 of 65

1.15

1.24

2.14e-05

CL:1312

Mixed, incl. PUA-like superfamily, and Polyol metabolic process

2 of 5

1.72

0.89

0.0167

CL:121

Translation, and RNA metabolic process

8 of 135

0.89

0.86

3.72e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

3 of 3

2.11

1.68

0.00056

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9635486

Infection with Mycobacterium tuberculosis

3 of 23

1.23

0.78

0.0118

MAP-5663205

Infectious disease

3 of 24

1.21

0.77

0.0118

MAP-1643685

Disease

3 of 24

1.21

0.77

0.0118

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0240

DNA-directed RNA polymerase

3 of 4

1.99

1.57

0.00078

KW-0804

Transcription

5 of 22

1.47

1.56

9.16e-05

KW-0548

Nucleotidyltransferase

3 of 11

1.55

1.05

0.0052

KW-0889

Transcription antitermination

2 of 2

2.11

1.05

0.0107

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