STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brca1Uncharacterized protein. (1180 aa)    
Predicted Functional Partners:
LOC109985360
BRCA1 associated RING domain 1.
   
0.999
ENSLBEP00000037734
SAE2 domain-containing protein.
   
 0.999
topbp1
DNA topoisomerase II binding protein 1.
   
 0.993
ENSLBEP00000029074
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 0.993
mre11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.993
babam1
BRISC and BRCA1 A complex member 1.
    
 0.993
ENSLBEP00000002749
Uncharacterized protein.
   
 0.991
LOC109984746
Tower domain-containing protein.
   
 0.991
brip1
BRCA1 interacting protein C-terminal helicase 1.
   
 0.991
rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 0.991
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.