LOC109980901 protein (Labrus bergylta) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

LOC109980901

Sulfotransferase; Belongs to the sulfotransferase 1 family. (340 aa)

Predicted Functional Partners:

sult4a1

0.690

LOC109999535

0.598

LOC109983308

0.598

LOC109983834

0.575

LOC109997998

0.564

LOC109983127

0.564

LOC110000510

0.564

sult6b1

0.562

LOC109997999

0.559

LOC109998600

0.558

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109980901	LOC109983127	ENSLBEP00000010615	ENSLBEP00000007156	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.564
LOC109980901	LOC109983308	ENSLBEP00000010615	ENSLBEP00000028889	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Cytochrome P450, family 1, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family.	0.598
LOC109980901	LOC109983834	ENSLBEP00000010615	ENSLBEP00000008976	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.575
LOC109980901	LOC109997998	ENSLBEP00000010615	ENSLBEP00000006977	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.564
LOC109980901	LOC109997999	ENSLBEP00000010615	ENSLBEP00000006948	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.559
LOC109980901	LOC109998600	ENSLBEP00000010615	ENSLBEP00000006946	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Hydroxysteroid (17-beta) dehydrogenase 7.	0.558
LOC109980901	LOC109999535	ENSLBEP00000010615	ENSLBEP00000023408	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.	0.598
LOC109980901	LOC110000510	ENSLBEP00000010615	ENSLBEP00000010698	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.564
LOC109980901	sult4a1	ENSLBEP00000010615	ENSLBEP00000037604	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.690
LOC109980901	sult6b1	ENSLBEP00000010615	ENSLBEP00000001467	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.562
LOC109983127	LOC109980901	ENSLBEP00000007156	ENSLBEP00000010615	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.564
LOC109983127	LOC109983308	ENSLBEP00000007156	ENSLBEP00000028889	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Cytochrome P450, family 1, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family.	0.633
LOC109983127	LOC109998600	ENSLBEP00000007156	ENSLBEP00000006946	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Hydroxysteroid (17-beta) dehydrogenase 7.	0.499
LOC109983127	LOC109999535	ENSLBEP00000007156	ENSLBEP00000023408	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.	0.633
LOC109983127	sult4a1	ENSLBEP00000007156	ENSLBEP00000037604	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.656
LOC109983127	sult6b1	ENSLBEP00000007156	ENSLBEP00000001467	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.570
LOC109983308	LOC109980901	ENSLBEP00000028889	ENSLBEP00000010615	Cytochrome P450, family 1, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.598
LOC109983308	LOC109983127	ENSLBEP00000028889	ENSLBEP00000007156	Cytochrome P450, family 1, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.633
LOC109983308	LOC109983834	ENSLBEP00000028889	ENSLBEP00000008976	Cytochrome P450, family 1, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.633
LOC109983308	LOC109997998	ENSLBEP00000028889	ENSLBEP00000006977	Cytochrome P450, family 1, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.633

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Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.763

expected number of edges:

13

PPI enrichment p-value:

3.18e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006520

Cellular amino acid metabolic process

6 of 216

1.59

1.79

4.03e-05

GO:1901606

Alpha-amino acid catabolic process

4 of 71

1.9

1.5

0.00093

GO:0009063

Cellular amino acid catabolic process

4 of 83

1.83

1.44

0.0011

GO:0019478

D-amino acid catabolic process

2 of 2

3.15

1.3

0.0045

GO:0006399

tRNA metabolic process

4 of 161

1.54

1.06

0.0049

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003884

D-amino-acid oxidase activity

2 of 2

3.15

1.16

0.0080

GO:0050660

Flavin adenine dinucleotide binding

3 of 73

1.76

0.92

0.0150

GO:0140101

Catalytic activity, acting on a tRNA

3 of 108

1.59

0.74

0.0319

GO:0043168

Anion binding

8 of 2034

0.74

0.49

0.0150

GO:0036094

Small molecule binding

8 of 2098

0.73

0.48

0.0150

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:12276

Mixed, incl. tRNA aminoacylation, and Regulation of mitochondrial translation

6 of 77

2.04

3.43

2.89e-08

CL:12406

Mixed, incl. Endoplasmic reticulum vesicle transporter , and tRNA wobble uridine modification

4 of 12

2.67

3.42

4.04e-07

CL:18828

Mixed, incl. One carbon pool by folate, and Glycine cleavage complex

3 of 24

2.24

1.74

0.00050

CL:18711

Alpha-amino acid metabolic process, and Cysteine and methionine metabolism

4 of 99

1.75

1.55

0.00048

CL:18860

Mixed, incl. D-amino-acid oxidase activity, and Electron-transferring-flavoprotein dehydrogenase activity

2 of 5

2.75

1.3

0.0044

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04146

Peroxisome

3 of 104

1.61

0.86

0.0177

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-71291

Metabolism of amino acids and derivatives

5 of 264

1.43

1.21

0.0011

MAP-9033241

Peroxisomal protein import

3 of 71

1.77

0.94

0.0142

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0820

tRNA-binding

2 of 12

2.37

1.19

0.0064

KW-0274

FAD

3 of 70

1.78

1.09

0.0064

KW-0819

tRNA processing

2 of 39

1.86

0.75

0.0370

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01266

FAD dependent oxidoreductase

2 of 4

2.85

1.05

0.0125

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