STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC109990669Serpin peptidase inhibitor, clade I (neuroserpin), member 1; Belongs to the serpin family. (395 aa)    
Predicted Functional Partners:
ENSLBEP00000006601
Hyaluronan binding protein 2.
  
 0.731
LOC109987245
Uncharacterized protein.
  
 0.731
hgfac
HGF activator.
  
 0.707
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.692
LOC109985336
Vitronectin b.
   
 0.605
LOC109987997
Vitronectin a.
   
 0.605
ENSLBEP00000014606
Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a; Belongs to the serpin family.
  
 
  0.577
LOC109996574
Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
   
 0.567
agtr1
Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family.
    
  0.559
atp6ap2
ATPase H+ transporting accessory protein 2.
   
 0.554
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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