STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC109981137G protein-coupled receptor kinase interacting ArfGAP 2b. (663 aa)    
Predicted Functional Partners:
LOC109980209
Uncharacterized protein.
    
 0.907
LOC109999324
Rho guanine nucleotide exchange factor (GEF) 7b.
    
 0.907
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
    
 0.907
arhgef7
Rho guanine nucleotide exchange factor (GEF) 7a.
    
 0.907
LOC109982075
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.906
pxn
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.906
LOC109994299
Leupaxin.
    
 0.906
TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
    
 0.906
arfgap1
ADP-ribosylation factor GTPase activating protein 1.
     
0.827
adsl
Adenylosuccinate lyase.
 
      0.812
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.