st3gal2 protein (Labrus bergylta) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

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Score

st3gal2

ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (333 aa)

Predicted Functional Partners:

c1galt1c1

0.889

LOC109980937

0.876

LOC109984447

0.876

st6galnac6

0.870

st8sia1

0.869

LOC109989417

0.866

LOC109995098

0.866

LOC109984472

0.864

LOC109984272

0.861

ENSLBEP00000012589

0.861

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000012589	LOC109980937	ENSLBEP00000012589	ENSLBEP00000010418	Uncharacterized protein.	Hexosyltransferase.	0.496
ENSLBEP00000012589	LOC109984447	ENSLBEP00000012589	ENSLBEP00000030609	Uncharacterized protein.	Hexosyltransferase.	0.496
ENSLBEP00000012589	LOC109989417	ENSLBEP00000012589	ENSLBEP00000004714	Uncharacterized protein.	Glucosaminyl (N-acetyl) transferase 4a.	0.878
ENSLBEP00000012589	LOC109995098	ENSLBEP00000012589	ENSLBEP00000037509	Uncharacterized protein.	Si:dkeyp-87d8.8.	0.878
ENSLBEP00000012589	c1galt1c1	ENSLBEP00000012589	ENSLBEP00000038491	Uncharacterized protein.	C1GALT1-specific chaperone 1.	0.895
ENSLBEP00000012589	st3gal2	ENSLBEP00000012589	ENSLBEP00000024120	Uncharacterized protein.	ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family.	0.861
LOC109980937	ENSLBEP00000012589	ENSLBEP00000010418	ENSLBEP00000012589	Hexosyltransferase.	Uncharacterized protein.	0.496
LOC109980937	LOC109984272	ENSLBEP00000010418	ENSLBEP00000009896	Hexosyltransferase.	Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a.	0.496
LOC109980937	LOC109989417	ENSLBEP00000010418	ENSLBEP00000004714	Hexosyltransferase.	Glucosaminyl (N-acetyl) transferase 4a.	0.439
LOC109980937	LOC109995098	ENSLBEP00000010418	ENSLBEP00000037509	Hexosyltransferase.	Si:dkeyp-87d8.8.	0.439
LOC109980937	c1galt1c1	ENSLBEP00000010418	ENSLBEP00000038491	Hexosyltransferase.	C1GALT1-specific chaperone 1.	0.617
LOC109980937	st3gal2	ENSLBEP00000010418	ENSLBEP00000024120	Hexosyltransferase.	ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family.	0.876
LOC109984272	LOC109980937	ENSLBEP00000009896	ENSLBEP00000010418	Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a.	Hexosyltransferase.	0.496
LOC109984272	LOC109984447	ENSLBEP00000009896	ENSLBEP00000030609	Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a.	Hexosyltransferase.	0.496
LOC109984272	LOC109989417	ENSLBEP00000009896	ENSLBEP00000004714	Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a.	Glucosaminyl (N-acetyl) transferase 4a.	0.878
LOC109984272	LOC109995098	ENSLBEP00000009896	ENSLBEP00000037509	Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a.	Si:dkeyp-87d8.8.	0.878
LOC109984272	c1galt1c1	ENSLBEP00000009896	ENSLBEP00000038491	Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a.	C1GALT1-specific chaperone 1.	0.895
LOC109984272	st3gal2	ENSLBEP00000009896	ENSLBEP00000024120	Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a.	ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family.	0.861
LOC109984447	ENSLBEP00000012589	ENSLBEP00000030609	ENSLBEP00000012589	Hexosyltransferase.	Uncharacterized protein.	0.496
LOC109984447	LOC109984272	ENSLBEP00000030609	ENSLBEP00000009896	Hexosyltransferase.	Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a.	0.496

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.968

expected number of edges:

43

PPI enrichment p-value:

0.736

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030176

Integral component of endoplasmic reticulum membrane

3 of 132

1.63

0.79

0.0265

GO:0005615

Extracellular space

6 of 1087

1.02

0.69

0.0095

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4709

Mixed, incl. Lipolysis stimulated receptor (LSR), and Kringle

6 of 10

3.05

6.91

1.44e-13

CL:4713

Kringle, and Establishment of epithelial cell apical/basal polarity

4 of 5

3.18

4.72

2.48e-09

CL:4690

Immunoglobulin C-2 Type, and Leucine rich repeat N-terminal domain

7 of 143

1.97

4.0

2.48e-10

CL:4409

MHC I, and MHC class I-like antigen recognition-like superfamily

2 of 6

2.8

1.44

0.0024

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0420

Kringle

3 of 19

2.47

2.27

5.53e-05

KW-0720

Serine protease

3 of 80

1.85

1.38

0.0016

KW-1015

Disulfide bond

6 of 1146

1.0

0.81

0.0016

KW-0245

EGF-like domain

3 of 226

1.4

0.8

0.0167

KW-0964

Secreted

3 of 242

1.37

0.79

0.0167

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038178

Kringle superfamily

3 of 19

2.47

1.77

0.00052

IPR000001

Kringle

3 of 19

2.47

1.77

0.00052

IPR013806

Kringle-like fold

3 of 28

2.31

1.74

0.00052

IPR003591

Leucine-rich repeat, typical subtype

5 of 199

1.68

1.6

0.00026

IPR001611

Leucine-rich repeat

5 of 270

1.54

1.4

0.00052

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00130

Kringle domain

3 of 19

2.47

2.24

6.46e-05

SM00013

Leucine rich repeat N-terminal domain

4 of 117

1.81

1.88

8.90e-05

SM00370

Leucine-rich repeats, outliers

5 of 233

1.61

1.75

6.30e-05

SM00369

Leucine-rich repeats, typical (most populated) subfamily

4 of 160

1.67

1.62

0.00023

SM00020

Trypsin-like serine protease

3 of 97

1.77

1.25

0.0027

(more ...)

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