STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM92BFamily with sequence similarity 92 member B. (316 aa)    
Predicted Functional Partners:
LOC109989387
RAN binding protein 2.
   
 0.721
ENSLBEP00000007600
Uncharacterized protein.
    
 
 0.630
ENSLBEP00000007705
annotation not available
    
 
 0.630
zfand4
Zinc finger, AN1-type domain 4.
    
 0.629
pibf1
Progesterone immunomodulatory binding factor 1.
    
 0.598
rabgef1
Uncharacterized protein.
    
 0.587
LOC110000582
Uncharacterized protein.
    
 0.587
LOC109977836
RAB guanine nucleotide exchange factor (GEF) 1.
    
 0.587
ENSLBEP00000029131
RAB guanine nucleotide exchange factor (GEF) 1, like.
    
 0.587
rnf8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
   
  0.568
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
Server load: low (20%) [HD]