STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC110003529Death-domain associated protein. (755 aa)    
Predicted Functional Partners:
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.988
ENSLBEP00000005682
Uncharacterized protein.
    
 0.974
atrx
ATRX chromatin remodeler.
    
 0.974
sumo1
Small ubiquitin-related modifier.
    
 0.972
LOC109981905
Uncharacterized protein.
    
 0.966
LOC109975131
Uncharacterized protein.
    
 0.966
mdm2
MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family.
    
 0.961
usp7
Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.
    
 0.959
ENSLBEP00000011240
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.956
LOC109988415
Mitogen-activated protein kinase kinase kinase 5.
    
 0.956
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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