STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC110004120E1A binding protein p300 b. (2680 aa)    
Predicted Functional Partners:
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.989
LOC109989542
CREB binding protein a.
  
0.986
LOC109994130
CREB binding protein b.
  
0.986
sp1
Sp1 transcription factor.
   
 0.984
LOC109989015
Interferon regulatory factor 3.
    
 0.981
mysm1
Myb-like, SWIRM and MPN domains 1.
   
 
 0.979
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.977
LOC109999233
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
    
 0.949
kat2a
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
    
 0.949
LOC109991266
Activating transcription factor 4a.
    
 0.941
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.