STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC109992736Uncharacterized protein. (203 aa)    
Predicted Functional Partners:
apaf1
Apoptotic peptidase activating factor 1.
    
 0.915
becn1
Beclin 1, autophagy related.
    
 0.910
bcl2l11
Uncharacterized protein.
    
 0.898
bad
BCL2 associated agonist of cell death b.
   
 0.881
tpx2
TPX2 microtubule nucleation factor.
    
 0.850
pink1
PTEN induced kinase 1.
    
 0.736
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.720
aifm1
Apoptosis inducing factor mitochondrion associated 1.
     
 0.662
pgam5
PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.
    
 0.657
tp73
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
    
 0.641
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.