node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APO65798.1 | kdsA | IE4872_CH00125 | IE4872_CH01957 | Protein involved in prephenate dehydratase activity and L-phenylalanine biosynthetic process. | 2-dehydro-3-deoxyphosphooctonate aldolase; Protein involved in catalytic activity and biosynthetic process; Belongs to the KdsA family. | 0.785 |
APO65798.1 | kdsB | IE4872_CH00125 | IE4872_CH00124 | Protein involved in prephenate dehydratase activity and L-phenylalanine biosynthetic process. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.777 |
APO66591.1 | APO67979.1 | IE4872_CH00938 | IE4872_CH02365 | 3-deoxy-D-manno-octulosonic-acid transferase protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Lipid A biosynthesis acyltransferase protein; Protein involved in transferase activity, transferring acyl groups and lipopolysaccharide core region biosynthetic process. | 0.983 |
APO66591.1 | kdsA | IE4872_CH00938 | IE4872_CH01957 | 3-deoxy-D-manno-octulosonic-acid transferase protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 2-dehydro-3-deoxyphosphooctonate aldolase; Protein involved in catalytic activity and biosynthetic process; Belongs to the KdsA family. | 0.854 |
APO66591.1 | kdsB | IE4872_CH00938 | IE4872_CH00124 | 3-deoxy-D-manno-octulosonic-acid transferase protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.985 |
APO66591.1 | kdsD | IE4872_CH00938 | IE4872_CH03583 | 3-deoxy-D-manno-octulosonic-acid transferase protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Arabinose 5-phosphate isomerase KdsD/KpsF; Protein involved in isomerase activity and carbohydrate metabolic process; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.839 |
APO66591.1 | lpxA | IE4872_CH00938 | IE4872_CH01949 | 3-deoxy-D-manno-octulosonic-acid transferase protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.857 |
APO66591.1 | lpxB | IE4872_CH00938 | IE4872_CH01951 | 3-deoxy-D-manno-octulosonic-acid transferase protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.859 |
APO66591.1 | lpxC | IE4872_CH00938 | IE4872_CH02605 | 3-deoxy-D-manno-octulosonic-acid transferase protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.857 |
APO66591.1 | lpxD | IE4872_CH00938 | IE4872_CH01947 | 3-deoxy-D-manno-octulosonic-acid transferase protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.857 |
APO66591.1 | lpxK | IE4872_CH00938 | IE4872_CH00940 | 3-deoxy-D-manno-octulosonic-acid transferase protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.997 |
APO67979.1 | APO66591.1 | IE4872_CH02365 | IE4872_CH00938 | Lipid A biosynthesis acyltransferase protein; Protein involved in transferase activity, transferring acyl groups and lipopolysaccharide core region biosynthetic process. | 3-deoxy-D-manno-octulosonic-acid transferase protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.983 |
APO67979.1 | kdsA | IE4872_CH02365 | IE4872_CH01957 | Lipid A biosynthesis acyltransferase protein; Protein involved in transferase activity, transferring acyl groups and lipopolysaccharide core region biosynthetic process. | 2-dehydro-3-deoxyphosphooctonate aldolase; Protein involved in catalytic activity and biosynthetic process; Belongs to the KdsA family. | 0.730 |
APO67979.1 | kdsB | IE4872_CH02365 | IE4872_CH00124 | Lipid A biosynthesis acyltransferase protein; Protein involved in transferase activity, transferring acyl groups and lipopolysaccharide core region biosynthetic process. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.773 |
APO67979.1 | kdsD | IE4872_CH02365 | IE4872_CH03583 | Lipid A biosynthesis acyltransferase protein; Protein involved in transferase activity, transferring acyl groups and lipopolysaccharide core region biosynthetic process. | Arabinose 5-phosphate isomerase KdsD/KpsF; Protein involved in isomerase activity and carbohydrate metabolic process; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.732 |
APO67979.1 | lpxA | IE4872_CH02365 | IE4872_CH01949 | Lipid A biosynthesis acyltransferase protein; Protein involved in transferase activity, transferring acyl groups and lipopolysaccharide core region biosynthetic process. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.789 |
APO67979.1 | lpxB | IE4872_CH02365 | IE4872_CH01951 | Lipid A biosynthesis acyltransferase protein; Protein involved in transferase activity, transferring acyl groups and lipopolysaccharide core region biosynthetic process. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.818 |
APO67979.1 | lpxC | IE4872_CH02365 | IE4872_CH02605 | Lipid A biosynthesis acyltransferase protein; Protein involved in transferase activity, transferring acyl groups and lipopolysaccharide core region biosynthetic process. | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.788 |
APO67979.1 | lpxD | IE4872_CH02365 | IE4872_CH01947 | Lipid A biosynthesis acyltransferase protein; Protein involved in transferase activity, transferring acyl groups and lipopolysaccharide core region biosynthetic process. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.795 |
APO67979.1 | lpxK | IE4872_CH02365 | IE4872_CH00940 | Lipid A biosynthesis acyltransferase protein; Protein involved in transferase activity, transferring acyl groups and lipopolysaccharide core region biosynthetic process. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.855 |