node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APO67676.1 | metG | IE4872_CH02059 | IE4872_CH02060 | Protein involved in endodeoxyribonuclease activity, producing 5'-phosphomonoesters. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.973 |
argS | gluQ | IE4872_CH01792 | IE4872_CH03827 | arginyl-tRNA synthetase; Protein involved in nucleotide binding, arginine-tRNA ligase activity, ATP binding and arginyl-tRNA aminoacylation. | glutamyl-Q tRNA(Asp) synthetase; Protein involved in nucleotide binding, ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds and tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.878 |
argS | ileS | IE4872_CH01792 | IE4872_CH00927 | arginyl-tRNA synthetase; Protein involved in nucleotide binding, arginine-tRNA ligase activity, ATP binding and arginyl-tRNA aminoacylation. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | 0.957 |
argS | leuS | IE4872_CH01792 | IE4872_CH04161 | arginyl-tRNA synthetase; Protein involved in nucleotide binding, arginine-tRNA ligase activity, ATP binding and arginyl-tRNA aminoacylation. | leucyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.881 |
argS | lysS | IE4872_CH01792 | IE4872_CH03702 | arginyl-tRNA synthetase; Protein involved in nucleotide binding, arginine-tRNA ligase activity, ATP binding and arginyl-tRNA aminoacylation. | lysyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.904 |
argS | metG | IE4872_CH01792 | IE4872_CH02060 | arginyl-tRNA synthetase; Protein involved in nucleotide binding, arginine-tRNA ligase activity, ATP binding and arginyl-tRNA aminoacylation. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.936 |
argS | proS | IE4872_CH01792 | IE4872_CH01530 | arginyl-tRNA synthetase; Protein involved in nucleotide binding, arginine-tRNA ligase activity, ATP binding and arginyl-tRNA aminoacylation. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.942 |
fmt | metG | IE4872_CH00460 | IE4872_CH02060 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.915 |
fmt | metH | IE4872_CH00460 | IE4872_CH02670 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.918 |
gluQ | argS | IE4872_CH03827 | IE4872_CH01792 | glutamyl-Q tRNA(Asp) synthetase; Protein involved in nucleotide binding, ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds and tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | arginyl-tRNA synthetase; Protein involved in nucleotide binding, arginine-tRNA ligase activity, ATP binding and arginyl-tRNA aminoacylation. | 0.878 |
gluQ | ileS | IE4872_CH03827 | IE4872_CH00927 | glutamyl-Q tRNA(Asp) synthetase; Protein involved in nucleotide binding, ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds and tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | 0.920 |
gluQ | leuS | IE4872_CH03827 | IE4872_CH04161 | glutamyl-Q tRNA(Asp) synthetase; Protein involved in nucleotide binding, ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds and tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | leucyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.883 |
gluQ | lysS | IE4872_CH03827 | IE4872_CH03702 | glutamyl-Q tRNA(Asp) synthetase; Protein involved in nucleotide binding, ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds and tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | lysyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.905 |
gluQ | metG | IE4872_CH03827 | IE4872_CH02060 | glutamyl-Q tRNA(Asp) synthetase; Protein involved in nucleotide binding, ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds and tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.909 |
gluQ | metH | IE4872_CH03827 | IE4872_CH02670 | glutamyl-Q tRNA(Asp) synthetase; Protein involved in nucleotide binding, ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds and tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.469 |
gluQ | proS | IE4872_CH03827 | IE4872_CH01530 | glutamyl-Q tRNA(Asp) synthetase; Protein involved in nucleotide binding, ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds and tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.899 |
ileS | argS | IE4872_CH00927 | IE4872_CH01792 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | arginyl-tRNA synthetase; Protein involved in nucleotide binding, arginine-tRNA ligase activity, ATP binding and arginyl-tRNA aminoacylation. | 0.957 |
ileS | gluQ | IE4872_CH00927 | IE4872_CH03827 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | glutamyl-Q tRNA(Asp) synthetase; Protein involved in nucleotide binding, ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds and tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.920 |
ileS | leuS | IE4872_CH00927 | IE4872_CH04161 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | leucyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.949 |
ileS | lysS | IE4872_CH00927 | IE4872_CH03702 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | lysyl-tRNA synthetase; Protein involved in nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding and tRNA aminoacylation for protein translation; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.934 |