node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purB | purD | IE4872_CH02183 | IE4872_CH00983 | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. | 0.941 |
purB | purE | IE4872_CH02183 | IE4872_CH03551 | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.932 |
purB | purF | IE4872_CH02183 | IE4872_CH01379 | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.958 |
purB | purH | IE4872_CH02183 | IE4872_CH04151 | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Protein involved in catalytic activity. | 0.993 |
purB | purK | IE4872_CH02183 | IE4872_CH03552 | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | N5-carboxyaminoimidazole ribonucleotide synthetase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.935 |
purB | purL | IE4872_CH02183 | IE4872_CH02195 | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.936 |
purB | purM | IE4872_CH02183 | IE4872_CH01427 | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine cyclo-ligase; Protein involved in catalytic activity and 'de novo' IMP biosynthetic process. | 0.916 |
purB | purN | IE4872_CH02183 | IE4872_CH01426 | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.884 |
purB | purQ | IE4872_CH02183 | IE4872_CH02190 | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.881 |
purB | purS | IE4872_CH02183 | IE4872_CH02189 | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.891 |
purD | purB | IE4872_CH00983 | IE4872_CH02183 | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.941 |
purD | purE | IE4872_CH00983 | IE4872_CH03551 | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
purD | purF | IE4872_CH00983 | IE4872_CH01379 | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.998 |
purD | purH | IE4872_CH00983 | IE4872_CH04151 | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Protein involved in catalytic activity. | 0.983 |
purD | purK | IE4872_CH00983 | IE4872_CH03552 | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. | N5-carboxyaminoimidazole ribonucleotide synthetase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.966 |
purD | purL | IE4872_CH00983 | IE4872_CH02195 | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.956 |
purD | purM | IE4872_CH00983 | IE4872_CH01427 | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. | Phosphoribosylformylglycinamidine cyclo-ligase; Protein involved in catalytic activity and 'de novo' IMP biosynthetic process. | 0.998 |
purD | purN | IE4872_CH00983 | IE4872_CH01426 | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | IE4872_CH00983 | IE4872_CH02190 | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.963 |
purD | purS | IE4872_CH00983 | IE4872_CH02189 | Protein involved in phosphoribosylamine-glycine ligase activity, ligase activity and purine base biosynthetic process; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.938 |