node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SYN_01299 | guaA | SYN_01299 | SYN_01626 | Prephenate dehydratase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.630 |
SYN_01299 | proA | SYN_01299 | SYN_02002 | Prephenate dehydratase. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.614 |
SYN_01299 | proB | SYN_01299 | SYN_01350 | Prephenate dehydratase. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.569 |
SYN_01299 | proC | SYN_01299 | SYN_02197 | Prephenate dehydratase. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.465 |
SYN_01299 | ribBA | SYN_01299 | SYN_02371 | Prephenate dehydratase. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.612 |
SYN_01299 | rplU | SYN_01299 | SYN_01353 | Prephenate dehydratase. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.519 |
SYN_01299 | rpmA | SYN_01299 | SYN_01352 | Prephenate dehydratase. | LSU ribosomal protein L27P; Belongs to the bacterial ribosomal protein bL27 family. | 0.552 |
SYN_02533 | proA | SYN_02533 | SYN_02002 | Metallo-beta-lactamase superfamily. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.433 |
SYN_02533 | proB | SYN_02533 | SYN_01350 | Metallo-beta-lactamase superfamily. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.519 |
SYN_02533 | proC | SYN_02533 | SYN_02197 | Metallo-beta-lactamase superfamily. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.512 |
SYN_02533 | ribBA | SYN_02533 | SYN_02371 | Metallo-beta-lactamase superfamily. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.567 |
guaA | SYN_01299 | SYN_01626 | SYN_01299 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Prephenate dehydratase. | 0.630 |
guaA | obg | SYN_01626 | SYN_01351 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP-binding protein CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.514 |
guaA | proA | SYN_01626 | SYN_02002 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.579 |
guaA | proB | SYN_01626 | SYN_01350 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.520 |
guaA | proC | SYN_01626 | SYN_02197 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.587 |
guaA | prs | SYN_01626 | SYN_02767 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.793 |
guaA | ribBA | SYN_01626 | SYN_02371 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.671 |
guaA | rpmA | SYN_01626 | SYN_01352 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | LSU ribosomal protein L27P; Belongs to the bacterial ribosomal protein bL27 family. | 0.613 |
obg | guaA | SYN_01351 | SYN_01626 | GTP-binding protein CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.514 |