STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYN_01833hesA/moeB/thiF type protein. (1158 aa)    
Predicted Functional Partners:
SYN_00441
thiS family protein.
  
 
 0.896
thiG
Thiazole biosynthesis protein thiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.863
SYN_01832
Hypothetical cytosolic protein.
       0.791
SYN_01831
Predicted hydrolase; Metallo-beta-lactamase superfamily.
 
     0.766
iscS
Cysteine desulfurase / selenocysteine lyase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 0.734
SYN_02126
Cysteine desulfurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
   
 0.734
SYN_01958
Molybdopterin converting factor, large subunit.
  
 0.724
SYN_01004
Protein involved in biosynthesis of molybdopterin.
  
 0.705
thiC
Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.700
SYN_01521
Phosphomethylpyrimidine kinase / hydroxymethylpyrimidine kinase; Bifunctional.
 
  
 0.669
Your Current Organism:
Syntrophus aciditrophicus
NCBI taxonomy Id: 56780
Other names: S. aciditrophicus SB, Syntrophus aciditrophicus SB, Syntrophus aciditrophicus str. SB, Syntrophus aciditrophicus strain SB
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