node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SYN_00426 | guaA | SYN_00426 | SYN_01626 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.929 |
SYN_00426 | guaB | SYN_00426 | SYN_00897 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.877 |
SYN_00426 | purA | SYN_00426 | SYN_00122 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.998 |
SYN_00426 | pyrF | SYN_00426 | SYN_01281 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.502 |
SYN_00426 | surE | SYN_00426 | SYN_01984 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.926 |
SYN_02030 | surE | SYN_02030 | SYN_01984 | Colligrin; Belongs to the CinA family. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.917 |
cmk | gmk | SYN_03196 | SYN_01279 | Cytidylate kinase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.531 |
cmk | guaA | SYN_03196 | SYN_01626 | Cytidylate kinase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.596 |
cmk | guaB | SYN_03196 | SYN_00897 | Cytidylate kinase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.480 |
cmk | pyrH | SYN_03196 | SYN_00920 | Cytidylate kinase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.439 |
cmk | surE | SYN_03196 | SYN_01984 | Cytidylate kinase. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.927 |
gmk | cmk | SYN_01279 | SYN_03196 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Cytidylate kinase. | 0.531 |
gmk | guaA | SYN_01279 | SYN_01626 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.971 |
gmk | guaB | SYN_01279 | SYN_00897 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.485 |
gmk | pyrF | SYN_01279 | SYN_01281 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.746 |
gmk | pyrH | SYN_01279 | SYN_00920 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.592 |
gmk | surE | SYN_01279 | SYN_01984 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.917 |
guaA | SYN_00426 | SYN_01626 | SYN_00426 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.929 |
guaA | cmk | SYN_01626 | SYN_03196 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Cytidylate kinase. | 0.596 |
guaA | gmk | SYN_01626 | SYN_01279 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.971 |