node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SYN_00150 | SYN_02272 | SYN_00150 | SYN_02272 | Heme export protein apocytochrome heme-lyase. | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | 0.946 |
SYN_00150 | hemA | SYN_00150 | SYN_02274 | Heme export protein apocytochrome heme-lyase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.591 |
SYN_02267 | SYN_02272 | SYN_02267 | SYN_02272 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | 0.995 |
SYN_02267 | SYN_02276 | SYN_02267 | SYN_02276 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Precorrin-2 dehydrogenase / Sirohydrochlorin ferrochelatase; Bifunctional. | 0.629 |
SYN_02267 | hemA | SYN_02267 | SYN_02274 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.866 |
SYN_02267 | hemC | SYN_02267 | SYN_02273 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
SYN_02267 | hemL | SYN_02267 | SYN_00583 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.993 |
SYN_02272 | SYN_00150 | SYN_02272 | SYN_00150 | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | Heme export protein apocytochrome heme-lyase. | 0.946 |
SYN_02272 | SYN_02267 | SYN_02272 | SYN_02267 | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.995 |
SYN_02272 | SYN_02276 | SYN_02272 | SYN_02276 | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | Precorrin-2 dehydrogenase / Sirohydrochlorin ferrochelatase; Bifunctional. | 0.999 |
SYN_02272 | SYN_03385 | SYN_02272 | SYN_03385 | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | Heme insertion protein; Bacterial system II. | 0.590 |
SYN_02272 | gltX1 | SYN_02272 | SYN_02557 | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | Glutamyl glutaminyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.462 |
SYN_02272 | gltX2 | SYN_02272 | SYN_01399 | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.462 |
SYN_02272 | hemA | SYN_02272 | SYN_02274 | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.974 |
SYN_02272 | hemC | SYN_02272 | SYN_02273 | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
SYN_02272 | hemL | SYN_02272 | SYN_00583 | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.881 |
SYN_02276 | SYN_02267 | SYN_02276 | SYN_02267 | Precorrin-2 dehydrogenase / Sirohydrochlorin ferrochelatase; Bifunctional. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.629 |
SYN_02276 | SYN_02272 | SYN_02276 | SYN_02272 | Precorrin-2 dehydrogenase / Sirohydrochlorin ferrochelatase; Bifunctional. | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Bifunctional. | 0.999 |
SYN_02276 | SYN_03385 | SYN_02276 | SYN_03385 | Precorrin-2 dehydrogenase / Sirohydrochlorin ferrochelatase; Bifunctional. | Heme insertion protein; Bacterial system II. | 0.800 |
SYN_02276 | hemA | SYN_02276 | SYN_02274 | Precorrin-2 dehydrogenase / Sirohydrochlorin ferrochelatase; Bifunctional. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.887 |