node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SYN_00445 | SYN_02527 | SYN_00445 | SYN_02527 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 0.925 |
SYN_00445 | SYN_02619 | SYN_00445 | SYN_02619 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | O-succinylbenzoate synthase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 0.629 |
SYN_00445 | ispH | SYN_00445 | SYN_02454 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.489 |
SYN_00445 | menA | SYN_00445 | SYN_02622 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 1,4-dihydroxy-2-naphthoate polyprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.924 |
SYN_00445 | menB | SYN_00445 | SYN_02400 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | Dihydroxynaphthoic acid synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.750 |
SYN_00445 | menD | SYN_00445 | SYN_02399 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | 0.763 |
SYN_00445 | menF | SYN_00445 | SYN_02398 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.420 |
SYN_00445 | menH | SYN_00445 | SYN_02621 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | Menaquinone biosynthesis related protein, hydrolase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.630 |
SYN_02527 | SYN_00445 | SYN_02527 | SYN_00445 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 0.925 |
SYN_02527 | SYN_02619 | SYN_02527 | SYN_02619 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | O-succinylbenzoate synthase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 0.555 |
SYN_02527 | ispH | SYN_02527 | SYN_02454 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.489 |
SYN_02527 | menA | SYN_02527 | SYN_02622 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 1,4-dihydroxy-2-naphthoate polyprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.927 |
SYN_02527 | menB | SYN_02527 | SYN_02400 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | Dihydroxynaphthoic acid synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.649 |
SYN_02527 | menD | SYN_02527 | SYN_02399 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | 0.717 |
SYN_02527 | menF | SYN_02527 | SYN_02398 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.412 |
SYN_02527 | menH | SYN_02527 | SYN_02621 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | Menaquinone biosynthesis related protein, hydrolase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.572 |
SYN_02619 | SYN_00445 | SYN_02619 | SYN_00445 | O-succinylbenzoate synthase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 0.629 |
SYN_02619 | SYN_02527 | SYN_02619 | SYN_02527 | O-succinylbenzoate synthase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 1,4-dihydroxy-2-naphthoate polyprenyltransferase. | 0.555 |
SYN_02619 | SYN_02620 | SYN_02619 | SYN_02620 | O-succinylbenzoate synthase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | O-succinylbenzoic acid--CoA ligase. | 0.990 |
SYN_02619 | menA | SYN_02619 | SYN_02622 | O-succinylbenzoate synthase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 1,4-dihydroxy-2-naphthoate polyprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.928 |