node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CLUMA_CG003253 | CLUMA_CG015057 | A0A1J1HPY8 | A0A1J1IPC1 | Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.815 |
CLUMA_CG003253 | CLUMA_CG019495 | A0A1J1HPY8 | A0A1J1J4Z4 | Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.978 |
CLUMA_CG003253 | CLUMA_CG020440 | A0A1J1HPY8 | A0A1J1J4Z3 | Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). | CLUMA_CG020440, isoform A. | 0.407 |
CLUMA_CG004522 | CLUMA_CG005967 | A0A1J1HRX4 | A0A1J1HWG4 | CLUMA_CG004522, isoform A. | CLUMA_CG005967, isoform A. | 0.878 |
CLUMA_CG004522 | CLUMA_CG015057 | A0A1J1HRX4 | A0A1J1IPC1 | CLUMA_CG004522, isoform A. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.862 |
CLUMA_CG004522 | CLUMA_CG018191 | A0A1J1HRX4 | A0A1J1J3M4 | CLUMA_CG004522, isoform A. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.889 |
CLUMA_CG004522 | CLUMA_CG019109 | A0A1J1HRX4 | A0A1J1J538 | CLUMA_CG004522, isoform A. | CLUMA_CG019109, isoform A. | 0.789 |
CLUMA_CG005967 | CLUMA_CG004522 | A0A1J1HWG4 | A0A1J1HRX4 | CLUMA_CG005967, isoform A. | CLUMA_CG004522, isoform A. | 0.878 |
CLUMA_CG005967 | CLUMA_CG015057 | A0A1J1HWG4 | A0A1J1IPC1 | CLUMA_CG005967, isoform A. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.895 |
CLUMA_CG005967 | CLUMA_CG017889 | A0A1J1HWG4 | A0A1J1IZ69 | CLUMA_CG005967, isoform A. | CLUMA_CG017889, isoform A. | 0.903 |
CLUMA_CG005967 | CLUMA_CG018191 | A0A1J1HWG4 | A0A1J1J3M4 | CLUMA_CG005967, isoform A. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.687 |
CLUMA_CG005967 | CLUMA_CG019109 | A0A1J1HWG4 | A0A1J1J538 | CLUMA_CG005967, isoform A. | CLUMA_CG019109, isoform A. | 0.892 |
CLUMA_CG005967 | CLUMA_CG020440 | A0A1J1HWG4 | A0A1J1J4Z3 | CLUMA_CG005967, isoform A. | CLUMA_CG020440, isoform A. | 0.790 |
CLUMA_CG013191 | CLUMA_CG015057 | A0A1J1II65 | A0A1J1IPC1 | CLUMA_CG013191, isoform A; Belongs to the spermidine/spermine synthase family. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.966 |
CLUMA_CG013191 | CLUMA_CG019495 | A0A1J1II65 | A0A1J1J4Z4 | CLUMA_CG013191, isoform A; Belongs to the spermidine/spermine synthase family. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.512 |
CLUMA_CG013191 | CLUMA_CG019578 | A0A1J1II65 | A0A1J1J2J3 | CLUMA_CG013191, isoform A; Belongs to the spermidine/spermine synthase family. | CLUMA_CG019578, isoform A. | 0.953 |
CLUMA_CG015057 | CLUMA_CG003253 | A0A1J1IPC1 | A0A1J1HPY8 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). | 0.815 |
CLUMA_CG015057 | CLUMA_CG004522 | A0A1J1IPC1 | A0A1J1HRX4 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | CLUMA_CG004522, isoform A. | 0.862 |
CLUMA_CG015057 | CLUMA_CG005967 | A0A1J1IPC1 | A0A1J1HWG4 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | CLUMA_CG005967, isoform A. | 0.895 |
CLUMA_CG015057 | CLUMA_CG013191 | A0A1J1IPC1 | A0A1J1II65 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | CLUMA_CG013191, isoform A; Belongs to the spermidine/spermine synthase family. | 0.966 |