STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLUMA_CG016369CLUMA_CG016369, isoform A. (636 aa)    
Predicted Functional Partners:
CLUMA_CG017162
CLUMA_CG017162, isoform A; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.843
CLUMA_CG008076
Small ubiquitin-related modifier.
    
 0.733
CLUMA_CG017173
Small ubiquitin-related modifier.
    
 0.733
CLUMA_CG001781
CLUMA_CG001781, isoform A.
    
 0.718
CLUMA_CG020592
CLUMA_CG020592, isoform A; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.644
CLUMA_CG017779
CLUMA_CG017779, isoform A.
    
 0.630
CLUMA_CG008012
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
   
 
 0.624
CLUMA_CG014275
CLUMA_CG014275, isoform A; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.598
CLUMA_CG012137
CLUMA_CG012137, isoform A; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.579
CLUMA_CG012816
CLUMA_CG012816, isoform A; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.579
Your Current Organism:
Clunio marinus
NCBI taxonomy Id: 568069
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