node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GCA_000406125_03613 | iscS | GCA_000406125_03613 | GCA_000406125_02940 | Unannotated protein. | Unannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.950 |
GCA_000406125_03613 | moaA | GCA_000406125_03613 | GCA_000406125_01570 | Unannotated protein. | Unannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.647 |
GCA_000406125_03613 | moaC | GCA_000406125_03613 | GCA_000406125_01572 | Unannotated protein. | Unannotated protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.629 |
GCA_000406125_03613 | moaD | GCA_000406125_03613 | GCA_000406125_01573 | Unannotated protein. | Unannotated protein. | 0.978 |
GCA_000406125_03613 | moaE | GCA_000406125_03613 | GCA_000406125_01574 | Unannotated protein. | Unannotated protein. | 0.850 |
GCA_000406125_03613 | moeA | GCA_000406125_03613 | GCA_000406125_01545 | Unannotated protein. | Unannotated protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.593 |
GCA_000406125_03613 | moeB | GCA_000406125_03613 | GCA_000406125_01544 | Unannotated protein. | Unannotated protein. | 0.926 |
GCA_000406125_03613 | thiG | GCA_000406125_03613 | GCA_000406125_00206 | Unannotated protein. | Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.896 |
GCA_000406125_03613 | thiI | GCA_000406125_03613 | GCA_000406125_01114 | Unannotated protein. | Unannotated protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.830 |
GCA_000406125_03613 | thiS | GCA_000406125_03613 | GCA_000406125_00207 | Unannotated protein. | Unannotated protein. | 0.854 |
iscS | GCA_000406125_03613 | GCA_000406125_02940 | GCA_000406125_03613 | Unannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Unannotated protein. | 0.950 |
iscS | moaC | GCA_000406125_02940 | GCA_000406125_01572 | Unannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Unannotated protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.451 |
iscS | moaD | GCA_000406125_02940 | GCA_000406125_01573 | Unannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Unannotated protein. | 0.716 |
iscS | moeB | GCA_000406125_02940 | GCA_000406125_01544 | Unannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Unannotated protein. | 0.968 |
iscS | thiG | GCA_000406125_02940 | GCA_000406125_00206 | Unannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.632 |
iscS | thiI | GCA_000406125_02940 | GCA_000406125_01114 | Unannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Unannotated protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.995 |
moaA | GCA_000406125_03613 | GCA_000406125_01570 | GCA_000406125_03613 | Unannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Unannotated protein. | 0.647 |
moaA | moaC | GCA_000406125_01570 | GCA_000406125_01572 | Unannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Unannotated protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.999 |
moaA | moaD | GCA_000406125_01570 | GCA_000406125_01573 | Unannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Unannotated protein. | 0.970 |
moaA | moaE | GCA_000406125_01570 | GCA_000406125_01574 | Unannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Unannotated protein. | 0.986 |