STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCL25494.1Hypothetical protein. (491 aa)    
Predicted Functional Partners:
SCL34929.1
Hypothetical protein.
  
     0.700
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.614
SCL23725.1
DNA topoisomerase IV subunit B.
    
 
 0.614
SCL26739.1
Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.578
SCL25501.1
Tetratricopeptide repeat-containing protein.
  
    0.566
SCL25506.1
Haloacid Dehalogenase Superfamily Class (subfamily) IIA/haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E.
  
    0.565
SCL17042.1
Hypothetical protein.
  
    0.550
SCL18494.1
Putative adhesin.
    
   0.478
SCL38543.1
Putative adhesin.
    
   0.478
SCL39543.1
Putative adhesin.
    
   0.478
Your Current Organism:
Micromonospora rhizosphaerae
NCBI taxonomy Id: 568872
Other names: CGMCC 4.5599, DSM 45431, JCM 17737, M. rhizosphaerae, Micromonospora rhizosphaerae Wang et al. 2011, Micromonospora sp. 211018, strain 211018
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.