node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDG93104.1 | SDH05541.1 | SAMN05192534_10148 | SAMN05192534_101465 | Dihydrolipoamide dehydrogenase. | Glutamate synthase (NADH) large subunit. | 0.934 |
SDG93104.1 | SDH51830.1 | SAMN05192534_10148 | SAMN05192534_106164 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.558 |
SDG93104.1 | gcvH | SAMN05192534_10148 | SAMN05192534_10837 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. | 0.874 |
SDG93104.1 | gcvPA | SAMN05192534_10148 | SAMN05192534_11748 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.841 |
SDG93104.1 | gcvPB | SAMN05192534_10148 | SAMN05192534_11747 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.844 |
SDG93104.1 | gcvT | SAMN05192534_10148 | SAMN05192534_11749 | Dihydrolipoamide dehydrogenase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.862 |
SDG93104.1 | glyA | SAMN05192534_10148 | SAMN05192534_11743 | Dihydrolipoamide dehydrogenase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.484 |
SDG93104.1 | glyA-2 | SAMN05192534_10148 | SAMN05192534_11942 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.484 |
SDH05541.1 | SDG93104.1 | SAMN05192534_101465 | SAMN05192534_10148 | Glutamate synthase (NADH) large subunit. | Dihydrolipoamide dehydrogenase. | 0.934 |
SDH05541.1 | SDH33177.1 | SAMN05192534_101465 | SAMN05192534_10464 | Glutamate synthase (NADH) large subunit. | Isocitrate dehydrogenase (NADP). | 0.962 |
SDH05541.1 | SDH51830.1 | SAMN05192534_101465 | SAMN05192534_106164 | Glutamate synthase (NADH) large subunit. | Dihydrolipoamide dehydrogenase. | 0.934 |
SDH05541.1 | gcvH | SAMN05192534_101465 | SAMN05192534_10837 | Glutamate synthase (NADH) large subunit. | Glycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. | 0.951 |
SDH05541.1 | gcvPA | SAMN05192534_101465 | SAMN05192534_11748 | Glutamate synthase (NADH) large subunit. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.954 |
SDH05541.1 | gcvPB | SAMN05192534_101465 | SAMN05192534_11747 | Glutamate synthase (NADH) large subunit. | Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.954 |
SDH05541.1 | gcvT | SAMN05192534_101465 | SAMN05192534_11749 | Glutamate synthase (NADH) large subunit. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.961 |
SDH05541.1 | glyA | SAMN05192534_101465 | SAMN05192534_11743 | Glutamate synthase (NADH) large subunit. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.921 |
SDH05541.1 | glyA-2 | SAMN05192534_101465 | SAMN05192534_11942 | Glutamate synthase (NADH) large subunit. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.921 |
SDH05541.1 | purD | SAMN05192534_101465 | SAMN05192534_11153 | Glutamate synthase (NADH) large subunit. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.590 |
SDH33177.1 | SDH05541.1 | SAMN05192534_10464 | SAMN05192534_101465 | Isocitrate dehydrogenase (NADP). | Glutamate synthase (NADH) large subunit. | 0.962 |
SDH33177.1 | gcvPB | SAMN05192534_10464 | SAMN05192534_11747 | Isocitrate dehydrogenase (NADP). | Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.730 |