STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANC40502.1Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (438 aa)    
Predicted Functional Partners:
ANC40767.1
Xanthine dehydrogenase FAD-binding subunit XdhB; FAD-binding subunit; with XdhA and XdhC participates in purine salvage; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.942
ANC40768.1
Xanthine dehydrogenase molybdenum-binding subunit XdhA; Molybdenum cofactor-binding protein; participates in purine salvage; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.932
ANC39073.1
Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.923
ANC40766.1
Xanthine dehydrogenase; Iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.921
ANC40845.1
Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.916
ANC40214.1
tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.907
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 
 0.905
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
     
 0.905
deoD
Purine-nucleoside phosphorylase; Catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
ppnP
Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
Your Current Organism:
Hafnia alvei
NCBI taxonomy Id: 569
Other names: ATCC 13337, CCUG 41547, CIP 57.31, DSM 30163, Enterobacter aerogenes subsp. hafniae, Enterobacter alvei, Enterobacter hafniae, H. alvei, Hafnia alvei sensu stricto genomosp. 1, LMG 10392, LMG:10392, NCDC 434-68, NCTC 8105, NRRL B-4260
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