STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q4D301_TRYCCTryparedoxin peroxidase, putative. (199 aa)    
Predicted Functional Partners:
TRS
Trypanothione synthetase; Bifunctional enzyme which catalyzes the formation of trypanothione (N(1),N(8)-bis(glutathionyl)spermidine) from glutathione and spermidine. Converts spermidine or glutathionylspermidine into trypanothione. Can also convert aminopropylcadaverine into glutothionylaminopropylcadaverine and homotrypanothione. Also has low amidase activity, hydrolyzing trypanothione, homotrypanothione or glutathionylspermidine to form glutathione and the corresponding polyamine; In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.
   
 0.960
Q4CL55_TRYCC
Trypanothione reductase, putative.
  
 0.885
Q4CMQ7_TRYCC
Trypanothione reductase, putative.
  
 0.885
Q4CT43_TRYCC
Trypanothione reductase, putative.
  
 0.885
Q4D1B8_TRYCC
Tryparedoxin, putative.
      
 0.804
Q4D1B9_TRYCC
Tryparedoxin, putative.
      
 0.804
Q4DE24_TRYCC
Uncharacterized protein.
  
 0.775
Q4DJ25_TRYCC
Thioredoxin; Belongs to the thioredoxin family.
  
 0.775
Q4DM29_TRYCC
Thioredoxin; Belongs to the thioredoxin family.
  
 0.775
Q4CVN4_TRYCC
Iron superoxide dismutase, putative.
  
 
 0.673
Your Current Organism:
Trypanosoma cruzi
NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.