node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KAE1 | PV07_02486 | A0A0D2BDA1 | A0A0D2CL20 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | 0.995 |
KAE1 | PV07_08853 | A0A0D2BDA1 | A0A0D2AL08 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | Protein kinase domain-containing protein. | 0.995 |
KAE1 | PV07_11118 | A0A0D2BDA1 | A0A0D2BWX8 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.524 |
KAE1 | PV07_11235 | A0A0D2BDA1 | A0A0D2BXI0 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | Uncharacterized protein. | 0.487 |
KAE1 | PV07_12468 | A0A0D2BDA1 | A0A0D2ABK8 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | Sua5/YciO/YrdC/YwlC family tRNA threonylcarbamoyl adenosine modification protein. | 0.866 |
PV07_02486 | KAE1 | A0A0D2CL20 | A0A0D2BDA1 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.995 |
PV07_02486 | PV07_08853 | A0A0D2CL20 | A0A0D2AL08 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | Protein kinase domain-containing protein. | 0.997 |
PV07_02486 | PV07_11118 | A0A0D2CL20 | A0A0D2BWX8 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.959 |
PV07_02486 | PV07_11235 | A0A0D2CL20 | A0A0D2BXI0 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | Uncharacterized protein. | 0.956 |
PV07_02486 | PV07_12468 | A0A0D2CL20 | A0A0D2ABK8 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | Sua5/YciO/YrdC/YwlC family tRNA threonylcarbamoyl adenosine modification protein. | 0.504 |
PV07_02882 | PV07_08853 | A0A0D1ZSZ6 | A0A0D2AL08 | Uncharacterized protein. | Protein kinase domain-containing protein. | 0.504 |
PV07_03342 | PV07_08853 | A0A0D2D7L8 | A0A0D2AL08 | Grx4 family monothiol glutaredoxin. | Protein kinase domain-containing protein. | 0.557 |
PV07_04262 | PV07_08853 | A0A0D2CRY6 | A0A0D2AL08 | Grx4 family monothiol glutaredoxin. | Protein kinase domain-containing protein. | 0.665 |
PV07_08853 | KAE1 | A0A0D2AL08 | A0A0D2BDA1 | Protein kinase domain-containing protein. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.995 |
PV07_08853 | PV07_02486 | A0A0D2AL08 | A0A0D2CL20 | Protein kinase domain-containing protein. | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | 0.997 |
PV07_08853 | PV07_02882 | A0A0D2AL08 | A0A0D1ZSZ6 | Protein kinase domain-containing protein. | Uncharacterized protein. | 0.504 |
PV07_08853 | PV07_03342 | A0A0D2AL08 | A0A0D2D7L8 | Protein kinase domain-containing protein. | Grx4 family monothiol glutaredoxin. | 0.557 |
PV07_08853 | PV07_04262 | A0A0D2AL08 | A0A0D2CRY6 | Protein kinase domain-containing protein. | Grx4 family monothiol glutaredoxin. | 0.665 |
PV07_08853 | PV07_11118 | A0A0D2AL08 | A0A0D2BWX8 | Protein kinase domain-containing protein. | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.960 |
PV07_08853 | PV07_11235 | A0A0D2AL08 | A0A0D2BXI0 | Protein kinase domain-containing protein. | Uncharacterized protein. | 0.954 |