STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV07_04041Phosphomethylpyrimidine kinase. (530 aa)    
Predicted Functional Partners:
PV07_08401
Hydroxyethylthiazole kinase.
 
 
 0.959
PV07_12214
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
    
 0.849
PV07_12309
Uncharacterized protein.
   
 
 0.843
PV07_04093
Uncharacterized protein.
 
      0.802
PV07_06641
Zn(2)-C6 fungal-type domain-containing protein.
   
 
 0.795
PV07_07447
LMWPc domain-containing protein.
    
  0.787
PV07_05010
Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...]
  
  
 0.783
PV07_01619
Alkaline phosphatase.
    
 0.779
PV07_06227
Uncharacterized protein; Belongs to the histidine acid phosphatase family.
     
 0.779
PV07_06158
Zn(2)-C6 fungal-type domain-containing protein.
    
  0.766
Your Current Organism:
Cladophialophora immunda
NCBI taxonomy Id: 569365
Other names: C. immunda, CBS 834.96, Cladophialophora sp. CBS 834.96, Cladophialophora sp. HB-2008
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.