STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APD08306.1Integrase/recombinase; Belongs to the 'phage' integrase family. (313 aa)    
Predicted Functional Partners:
APD08307.1
NAD binding domain of 6-phosphogluconate dehydrogenase.
       0.615
APD08308.1
Ribonuclease activity regulator protein RraA.
       0.615
APD08309.1
LmbE-like protein.
       0.615
APD08310.1
Hypothetical protein.
       0.615
APD08311.1
GntR family transcriptional regulator.
       0.615
APD08312.1
Metapyrocatechase (catechol 2,3-dioxygenase).
  
    0.615
APD10034.1
Cell division protein FtsK; Belongs to the FtsK/SpoIIIE/SftA family.
 
   
 0.615
topA
DNA topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
 
  
 0.552
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.548
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.503
Your Current Organism:
Thermus brockianus
NCBI taxonomy Id: 56956
Other names: JCM 11602, NCIB 12676, NCIB:12676, NCIMB 12676, T. brockianus, strain YS38
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.