STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APD09486.1Isochorismatase. (196 aa)    
Predicted Functional Partners:
APD09483.1
Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.
  
    0.789
APD09485.1
DNA-3-methyladenine glycosidase.
       0.778
APD09484.1
Hypothetical protein.
       0.773
APD10235.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
  
 0.599
APD08728.1
Dihydropteridine/dihydrofolate reductase.
  
 0.570
APD09487.1
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
    0.564
nnr
Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to al [...]
  
    0.514
birA
Biotin operon repressor/biotin-[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.500
APD08946.1
Competence/damage-inducible protein CinA; Belongs to the CinA family.
     
 0.498
APD08271.1
Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
   
 
 0.451
Your Current Organism:
Thermus brockianus
NCBI taxonomy Id: 56956
Other names: JCM 11602, NCIB 12676, NCIB:12676, NCIMB 12676, T. brockianus, strain YS38
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