STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gtfA1_2Glycosyl transferase family 4; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. (502 aa)    
Predicted Functional Partners:
gtfB_2
Glycosyl transferase family 8; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.
 
 
 0.992
gtfB_1
Glycosyl transferase family 8; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.
 
 
 0.967
asp2_3
Accessory secretory protein Asp2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.934
asp2_1
Accessory secretory protein Asp2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.934
secA2_2
Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
   
 
 0.849
asp1_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.786
asp1_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.786
secY-2
Preprotein translocase subunit SecY; Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel.
 
   
 0.657
secY
Preprotein translocase subunit SecY; Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel.
 
   
 0.652
KIX91224.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.648
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.