Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gppAExopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)    
Predicted Functional Partners:
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
  
 0.961
relA1
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.946
ywaC
GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.918
relA2
GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.918
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.835
KIX91838.1
phosphate:AMP phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.750
KIX91425.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.594
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.465
yrrB
Tetratricopeptide domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.417
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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