Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rpoEDNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (179 aa)    
Predicted Functional Partners:
KIX91334.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.759
KIX91433.1
Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.752
mecA
Competence negative regulator MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
  
     0.735
dnaD
Chromosome replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.731
yutD
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.726
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
    0.711
yqeH
GTPase; In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.673
KIX89892.1
DNA replication protein YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
     0.652
dnaI
Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.622
KIX91665.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.587
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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