STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
rsbUSerine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)    
Predicted Functional Partners:
rsbV
anti-sigma-B factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
 0.997
rsbW
Serine/threonine protein kinase; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
 
 0.997
sigB
RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.964
ribA
GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
  0.816
yhgF
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.670
mazE
Antitoxin MazE; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.668
mazF_2
PemK family transcriptional regulator; Toxic component of a type II toxin-antitoxin (TA) system.
       0.668
yrrB
Tetratricopeptide domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.645
KIX91380.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.628
alrA
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
    0.625
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.